CEP95 antibody (AA 560-640)

Catalog No. ABIN7214026

This Rabbit Polyclonal antibody specifically detects CEP95 in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CEP95 antibody (AA 560-640) (ABIN7214026)

Target: CEP95 (Centrosomal Protein 95kDa (CEP95))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP95 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CEP95 Antibody

Binding Specificity: AA 560-640

Purpose: CCDC45 Polyclonal Antibody

Specificity: CCDC45 Polyclonal Antibody detects endogenous levels of CCDC45 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CCDC45 at AA range: 560-640

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CEP95

Target: CEP95 (Centrosomal Protein 95kDa (CEP95))

Alternative Name: CCDC45

Background: Rabbit Anti-CCDC45 Polyclonal Antibody,CEP95, CCDC45, CEP45, Centrosomal protein of 95 kDa, Coiled-coil domain-containing protein 45,The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC45 (coiled-coil domain containing 45) is a 821 amino acid protein encoded by a gene that maps to human chromosome 17q23.3. Chromosome 17 comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.,Centrosomal protein of 95 kDa

Molecular Weight: observerd band 95kDa

Gene ID: 90799

UniProt: Q96GE4