CLCN2 antibody

Catalog No. ABIN7227936

This anti-CLCN2 antibody is a Rabbit Polyclonal antibody detecting CLCN2 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for CLCN2 antibody (ABIN7227936)

Target: CLCN2 (Chloride Channel 2 (CLCN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CLCN2 Antibody

Purpose: CLCN2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CLCN2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CLCN2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CLCN2

Target: CLCN2 (Chloride Channel 2 (CLCN2))

Alternative Name: CLCN2

Background: Rabbit Anti-CLCN2 Polyclonal Antibody,Chloride channel protein 2, ClC-2,CLCN2 (Chloride Voltage-Gated Channel 2) is a Protein Coding gene. Diseases associated with CLCN2 include Leukoencephalopathy With Ataxia and Epilepsy, Idiopathic Generalized 11. Among its related pathways are Hepatic ABC Transporters and Activation of cAMP-Dependent PKA. CLCN2 encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in CLCN2 may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for CLCN2.,CLCN2

Molecular Weight: observerd band 98kDa

Gene ID: 1181

UniProt: P51788