CDYL2 antibody (AA 1-80)

Catalog No. ABIN7214140

This Rabbit Polyclonal antibody specifically detects CDYL2 in WB, ELISA, ICC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CDYL2 antibody (AA 1-80) (ABIN7214140)

Target: CDYL2 (Chromodomain Protein, Y-Like 2 (CDYL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDYL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CDYL2 Antibody

Binding Specificity: AA 1-80

Purpose: CDYL2 Polyclonal Antibody

Specificity: CDYL2 Polyclonal Antibody detects endogenous levels of CDYL2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human CDYL2 at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ICC (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CDYL2

Target: CDYL2 (Chromodomain Protein, Y-Like 2 (CDYL2))

Alternative Name: CDYL2

Background: Rabbit Anti-CDYL2 Polyclonal Antibody,CDYL2, Chromodomain Y-like protein 2, CDY-like 2,CDY, a gene family expressed exclusively in the testis, localizes to a region of the Y chromosome frequently deleted in infertile males. CDY protein contains two functional domains, an N-terminal chromodomain, possibly functioning in heterochromatin interactions, and also a C-terminal domain which resembles enoyl-CoA-isomerase, a protein involved in fatty acid oxidation. Furthermore, CDY acts as a histone acetyltransferase, with strong preference for histone H4, a process required for the histone to proamine transition in spermatogenesis, consistent with the association with male infertility. Chromodomain Y-like protein (CDYL) is a related ubiquitous nuclear protein expressed at moderate levels in most tissues. The gene encoding for the CDYL protein localizes to chromosome 6p25.1.,Chromodomain Y-like protein 2

Molecular Weight: observerd band 56kDa

Gene ID: 124359

UniProt: Q8N8U2