NREP antibody (AA 30-110)

Catalog No. ABIN7225938

The Rabbit Polyclonal anti-NREP antibody has been validated for ELISA and IHC (p). It is suitable to detect NREP in samples from Human, Mouse and Rat.

Quick Overview for NREP antibody (AA 30-110) (ABIN7225938)

Target: NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NREP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NREP Antibody

Binding Specificity: AA 30-110

Purpose: P311 Polyclonal Antibody

Specificity: P311 Polyclonal Antibody detects endogenous levels of P311 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human P311 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for NREP

Target: NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))

Alternative Name: P311

Background: Rabbit Anti-P311 Polyclonal Antibody,NREP, C5orf13, P311, Neuronal regeneration-related protein, Neuronal protein 3.1, Protein p311,P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration and the differentiation of fibroblasts into myofibroblasts. Ser-59 phosphorylation decreases P311 stability, the gene encoding P311 maps to human chromosome 5q22.,Neuronal regeneration-related protein

Gene ID: 9315

UniProt: Q16612