Clusterin antibody (AA 370-450)
Quick Overview for Clusterin antibody (AA 370-450) (ABIN7214254)
Target
See all Clusterin (CLU) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 370-450
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Purpose
- Clusterin Polyclonal Antibody
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Specificity
- Clusterin Polyclonal Antibody detects endogenous levels of Clusterin protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the C-terminal region of human Clusterin at AA range: 370-450
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Clusterin (CLU)
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Alternative Name
- Clusterin
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Background
- Rabbit Anti-Clusterin Polyclonal Antibody,CLU, APOJ, CLI, KUB1, AAG4, Clusterin, Aging-associated gene 4 protein, Apolipoprotein J, Apo-J, Complement cytolysis inhibitor, CLI, Complement-associated protein SP-40, 40, Ku70-binding protein 1, NA1/NA2, Testosterone-repressed prostate m,Clusterin encoded by CLU is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.,Clusterin
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Molecular Weight
- observerd band 52kDa
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Gene ID
- 1191
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UniProt
- P10909
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Pathways
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
Target
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