CIRBP antibody

Catalog No. ABIN7227910

This Rabbit Polyclonal antibody specifically detects CIRBP in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CIRBP antibody (ABIN7227910)

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIRBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CIRBP Antibody

Purpose: CIRBP Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CIRBP protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CIRBP protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CIRBP

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Alternative Name: CIRBP

Background: Rabbit Anti-CIRBP Polyclonal Antibody,Cold-inducible RNA-binding protein, A18 hnRNP, Glycine-rich RNA-binding protein CIRP,CIRBP (Cold Inducible RNA Binding Protein) is a Protein Coding gene. Diseases associated with CIRBP include Cryptorchidism. Among its related pathways are DNA Damage and Translational Control. Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3-untranslated regions (3-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.,CIRBP

Molecular Weight: observerd band 18kDa

Gene ID: 1153

UniProt: Q14011

Pathways: Ribonucleoprotein Complex Subunit Organization