C1S antibody (Cleaved-Arg437)

Catalog No. ABIN7212432

This Rabbit Polyclonal antibody specifically detects C1S in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for C1S antibody (Cleaved-Arg437) (ABIN7212432)

Target: C1S (Complement Component 1, S Subcomponent (C1S))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1S antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-C1S Antibody

Binding Specificity: AA 360-440, Cleaved-Arg437

Purpose: Cleaved-C1s HC (R437) Polyclonal Antibody

Specificity: Cleaved-C1s HC (R437) Polyclonal Antibody detects endogenous levels of fragment of activated C1s HC protein resulting from cleavage adjacent to R437.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human C1s HC at AA range: 360-440

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for C1S

Target: C1S (Complement Component 1, S Subcomponent (C1S))

Alternative Name: C1s HC

Background: Rabbit Anti-Cleaved-C1s HC (R437) Polyclonal Antibody,C1S, Complement C1s subcomponent, C1 esterase, Complement component 1 subcomponent s,C1S encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in C1S are the cause of selective C1s deficiency.,Complement C1s subcomponent

Molecular Weight: observerd band 47+76kDa

Gene ID: 716

UniProt: P09871

Pathways: Complement System