Cullin 3 antibody (AA 1-80)

Catalog No. ABIN7214382

This Rabbit Polyclonal antibody specifically detects Cullin 3 in WB, ELISA and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for Cullin 3 antibody (AA 1-80) (ABIN7214382)

Target: Cullin 3 (CUL3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Cullin 3 Antibody

Binding Specificity: AA 1-80

Purpose: CUL-3 Polyclonal Antibody

Specificity: CUL-3 Polyclonal Antibody detects endogenous levels of CUL-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human CUL-3 at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Cullin 3

Target: Cullin 3 (CUL3)

Alternative Name: CUL-3

Background: Rabbit Anti-CUL-3 Polyclonal Antibody,CUL3, KIAA0617, Cullin-3, CUL-3,CUL3 encodes a member of the cullin protein family. Cullin 3 plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for CUL3.,Cullin-3

Molecular Weight: observerd band 90kDa

Gene ID: 8452

UniProt: Q13618

Pathways: M Phase