Cullin 7 antibody (AA 1570-1650)

Catalog No. ABIN7228102

The Rabbit Polyclonal anti-Cullin 7 antibody has been validated for WB and ELISA. It is suitable to detect Cullin 7 in samples from Human and Mouse.

Quick Overview for Cullin 7 antibody (AA 1570-1650) (ABIN7228102)

Target: Cullin 7 (CUL7)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cullin 7 Antibody

Binding Specificity: AA 1570-1650

Purpose: CUL7 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CUL7 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CUL7 protein at AA range: 1570-1650

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Cullin 7

Target: Cullin 7 (CUL7)

Alternative Name: CUL7

Background: Rabbit Anti-CUL7 Polyclonal Antibody,Cullin-7, CUL-7,The protein encoded by CUL7 (Cullin 7) is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in CUL7 are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for CUL7. CUL7 is a Protein Coding gene. Diseases associated with CUL7 include 3-M Syndrome 1 and 3-M Syndrome, Cul7-Related. Among its related pathways are Class I MHC mediated antigen processing and presentation and Unfolded Protein Response (UPR).,CUL7

Molecular Weight: observerd band 186kDa

Gene ID: 9820

UniProt: Q14999

Pathways: ER-Nucleus Signaling