CDKL4 antibody (AA 240-320)
Quick Overview for CDKL4 antibody (AA 240-320) (ABIN7214136)
Target
See all CDKL4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 240-320
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Purpose
- CdkL4 Polyclonal Antibody
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Specificity
- CdkL4 Polyclonal Antibody detects endogenous levels of CdkL4 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the C-terminal region of human CdkL4 at AA range: 240-320
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CDKL4 (Cyclin-Dependent Kinase-Like 4 (CDKL4))
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Alternative Name
- CdkL4
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Background
- Rabbit Anti-CdkL4 Polyclonal Antibody,CDKL4, Cyclin-dependent kinase-like 4,Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Cdks are considered potential targets for anti-cancer therapy due to their involvement with cell cycle regulation. Cdks are also involved in the regulation of transcription and mRNA processing. CdkL4 (cyclin-dependent kinase-like 4) is a 315 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family and may be involved in cell cycle regulation.,Cyclin-dependent kinase-like 4
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Molecular Weight
- observerd band 36kDa
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Gene ID
- 344387
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UniProt
- Q5MAI5
Target
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