PPIB antibody (C-Term)

Catalog No. ABIN7218394

This anti-PPIB antibody is a Rabbit Polyclonal antibody detecting PPIB in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for PPIB antibody (C-Term) (ABIN7218394)

Target: PPIB (Cyclophilin B (PPIB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PPIB Antibody

Binding Specificity: C-Term

Purpose: CyPB Polyclonal Antibody

Specificity: CyPB Polyclonal Antibody detects endogenous levels of CyPB protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human CyPB

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PPIB

Target: PPIB (Cyclophilin B (PPIB))

Alternative Name: CyPB

Background: Rabbit Anti-CyPB Polyclonal Antibody,PPIB, CYPB, Peptidyl-prolyl cis-trans isomerase B, PPIase B, CYP-S1, Cyclophilin B, Rotamase B, S-cyclophilin, SCYLP,Peptidyl-prolyl cis-trans isomerase B encoded by PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.,Peptidyl-prolyl cis-trans isomerase B

Molecular Weight: observerd band 24kDa

Gene ID: 5479

UniProt: P23284