CST6 antibody (Internal Region)

Catalog No. ABIN7219790

This anti-CST6 antibody is a Rabbit Polyclonal antibody detecting CST6 in ELISA and IHC (p). Suitable for Human.

Quick Overview for CST6 antibody (Internal Region) (ABIN7219790)

Target: CST6 (Cystatin E/M (CST6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CST6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CST6 Antibody

Binding Specificity: Internal Region

Purpose: Cystatin E/M Polyclonal Antibody

Specificity: Cystatin E/M Polyclonal Antibody detects endogenous levels of Cystatin E/M protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Cystatin E/M

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CST6

Target: CST6 (Cystatin E/M (CST6))

Alternative Name: Cystatin E/M

Background: Rabbit Anti-Cystatin E/M Polyclonal Antibody,CST6, Cystatin-M, Cystatin-6, Cystatin-E,The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.,Cystatin-M

Gene ID: 1474

UniProt: Q15828