CRLF1 antibody (AA 50-130)

Catalog No. ABIN7228058

This Rabbit Polyclonal antibody specifically detects CRLF1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for CRLF1 antibody (AA 50-130) (ABIN7228058)

Target: CRLF1 (Cytokine Receptor-Like Factor 1 (CRLF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRLF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CRLF1 Antibody

Binding Specificity: AA 50-130

Purpose: CRLF1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CRLF1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CRLF1 protein at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CRLF1

Target: CRLF1 (Cytokine Receptor-Like Factor 1 (CRLF1))

Alternative Name: CRLF1

Background: Rabbit Anti-CRLF1 Polyclonal Antibody,Cytokine receptor-like factor 1, Cytokine-like factor 1, ZcytoR5,CRLF1 (Cytokine Receptor Like Factor 1) is a Protein Coding gene. Diseases associated with CRLF1 include Cold-Induced Sweating Syndrome 1 and Crlf1-Related Cold-Induced Sweating Syndrome Including Crisponi Syndrome. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. CRLF1 encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in CRLF1 result in Crisponi syndrome and cold-induced sweating syndrome.,CRLF1

Molecular Weight: observerd band 46kDa

Gene ID: 9244

UniProt: O75462