CRTAM antibody (AA 260-340)

Catalog No. ABIN7228068

This anti-CRTAM antibody is a Rabbit Polyclonal antibody detecting CRTAM in ELISA and WB. Suitable for Human and Mouse.

Quick Overview for CRTAM antibody (AA 260-340) (ABIN7228068)

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTAM antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CRTAM Antibody

Binding Specificity: AA 260-340

Purpose: CRTAM Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CRTAM protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CRTAM protein at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CRTAM

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Alternative Name: CRTAM

Background: Rabbit Anti-CRTAM Polyclonal Antibody,Class-I MHC-restricted T-cell-associated molecule, CD_antigen: CD355,CRTAM (Cytotoxic And Regulatory T-Cell Molecule) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Innate Immune System. GO annotations related to this gene include receptor binding. An important paralog of this gene is CADM1. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.,CRTAM

Molecular Weight: observerd band 43kDa

Gene ID: 56253

UniProt: O95727

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation