DENND5A antibody (AA 650-730)

Catalog No. ABIN7228184

This Rabbit Polyclonal antibody specifically detects DENND5A in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for DENND5A antibody (AA 650-730) (ABIN7228184)

Target: DENND5A (DENN/MADD Domain Containing 5A (DENND5A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DENND5A antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-DENND5A Antibody

Binding Specificity: AA 650-730

Purpose: DEN5A Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DEN5A protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human DEN5A protein at AA range: 650-730

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for DENND5A

Target: DENND5A (DENN/MADD Domain Containing 5A (DENND5A))

Alternative Name: DEN5A

Background: Rabbit Anti-DEN5A Polyclonal Antibody,DENN domain-containing protein 5A, Rab6-interacting protein 1, Rab6IP1,DENND5A (DENN Domain Containing 5A) encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in DENND5A are associated with early infantile epileptic encephalopathy-49.,DEN5A

Molecular Weight: observerd band 141kDa

Gene ID: 23258

UniProt: Q6IQ26