DKK2 antibody
Quick Overview for DKK2 antibody (ABIN7228226)
Target
See all DKK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- DKK2 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of DKK2 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human DKK2 protein
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DKK2 (Dickkopf 2 Homolog (DKK2))
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Alternative Name
- DKK2
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Background
- Rabbit Anti-DKK2 Polyclonal Antibody,Dickkopf-related protein 2, Dickkopf-2, Dkk-2, hDkk-2,DKK2 encodes Dickkopf WNT Signaling Pathway Inhibitor 2 that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).,DKK2
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Molecular Weight
- observerd band 28kDa
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Gene ID
- 27123
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UniProt
- Q9UBU2
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Pathways
- WNT Signaling
Target
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