DAB1 antibody
Quick Overview for DAB1 antibody (ABIN7214504)
Target
See all DAB1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Dab1 Polyclonal Antibody
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Specificity
- Dab1 Polyclonal Antibody detects endogenous levels of Dab1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from human Dab1 around the non-phosphorylation site of Y232
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))
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Alternative Name
- Dab1
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Background
- Rabbit Anti-Dab1 Polyclonal Antibody,DAB1, Disabled homolog 1,The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. DAB1 is similar to disabled-1, and the protein encoded by DAB1 is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of DAB1 have been reported, but their full length nature has not been determined.,Disabled homolog 1
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Molecular Weight
- observerd band 60kDa
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Gene ID
- 1600
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UniProt
- O75553
Target
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