DVL2 antibody (AA 670-750)

Catalog No. ABIN7220106

The Rabbit Polyclonal anti-DVL2 antibody is suitable to detect DVL2 in samples from Human and Mouse. It has been validated for WB, ELISA and IHC (p).

Quick Overview for DVL2 antibody (AA 670-750) (ABIN7220106)

Target: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DVL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DVL2 Antibody

Binding Specificity: AA 670-750

Purpose: Dvl-2 Polyclonal Antibody

Specificity: Dvl-2 Polyclonal Antibody detects endogenous levels of Dvl-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Dvl-2 at AA range: 670-750

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for DVL2

Target: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Alternative Name: Dvl-2

Background: Rabbit Anti-Dvl-2 Polyclonal Antibody,DVL2, Segment polarity protein dishevelled homolog DVL-2, Dishevelled-2, DSH homolog 2,DVL2 encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40 % amino acid sequence similarity with Drosophila dsh. DVL2 encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.,Segment polarity protein dishevelled homolog DVL-2

Molecular Weight: observerd band 80kDa

Gene ID: 1856

UniProt: O14641

Pathways: Tube Formation