DNAI1 antibody (AA 180-260)
Quick Overview for DNAI1 antibody (AA 180-260) (ABIN7221084)
Target
See all DNAI1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 180-260
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Purpose
- Dynein IC1 Polyclonal Antibody
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Specificity
- Dynein IC1 Polyclonal Antibody detects endogenous levels of Dynein IC1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human Dynein IC1 at AA range: 180-260
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DNAI1 (Dynein, Axonemal, Intermediate Chain 1 (DNAI1))
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Alternative Name
- Dynein IC1
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Background
- Rabbit Anti-Dynein IC1 Polyclonal Antibody,DNAI1, Dynein intermediate chain 1, axonemal, Axonemal dynein intermediate chain 1,DNAI1 encodes a member of the dynein intermediate chain family. The dynein axonemal intermediate chain 1 is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants.,Dynein intermediate chain 1 axonemal
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Molecular Weight
- observerd band 79kDa
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Gene ID
- 27019
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UniProt
- Q9UI46
Target
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