EDAR antibody (AA 50-130)

Catalog No. ABIN7228346

This Rabbit Polyclonal antibody specifically detects EDAR in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for EDAR antibody (AA 50-130) (ABIN7228346)

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDAR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EDAR Antibody

Binding Specificity: AA 50-130

Purpose: EDAR Polyclonal Antibody

Specificity: The antibody detects endogenous levels of EDAR protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human EDAR protein at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for EDAR

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Alternative Name: EDAR

Background: Rabbit Anti-EDAR Polyclonal Antibody,Tumor necrosis factor receptor superfamily member EDAR, Anhidrotic ectodysplasin receptor 1, Downless homolog, EDA-A1 receptor, Ectodermal dysplasia receptor, Ectodysplasin-A receptor,EDAR encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in EDAR result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.,EDAR

Molecular Weight: observerd band 49kDa

Gene ID: 10913

UniProt: Q9UNE0

Pathways: Tube Formation, Ubiquitin Proteasome Pathway