EMID1 antibody (AA 690-770)

Catalog No. ABIN7227996

This Rabbit Polyclonal antibody specifically detects EMID1 in WB and ELISA. It exhibits reactivity toward Rat, Human and Mouse.

Quick Overview for EMID1 antibody (AA 690-770) (ABIN7227996)

Target: EMID1 (EMI Domain Containing 1 (EMID1))

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EMID1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EMID1 Antibody

Binding Specificity: AA 690-770

Purpose: CO5 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CO5 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CO5 protein at AA range: 690-770

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for EMID1

Target: EMID1 (EMI Domain Containing 1 (EMID1))

Alternative Name: CO5

Background: Rabbit Anti-CO5 Polyclonal Antibody,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4,C5 encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in C5 cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.,CO5

Molecular Weight: observerd band 184kDa

Gene ID: 727

UniProt: P01031