EPAS1 antibody (acLys385)

Catalog No. ABIN7226780

The Rabbit Polyclonal anti-EPAS1 antibody has been validated for WB and ELISA. It is suitable to detect EPAS1 in samples from Human, Rat and Mouse.

Quick Overview for EPAS1 antibody (acLys385) (ABIN7226780)

Target: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPAS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EPAS1 Antibody

Binding Specificity: acLys385

Purpose: Acetyl-EPAS-1 (K385) Polyclonal Antibody

Specificity: Acetyl-EPAS-1 (K385) Polyclonal Antibody detects endogenous levels of Acetyl-EPAS-1 (K385).

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthetic Peptide of Acetyl-EPAS-1 (K385)

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for EPAS1

Target: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Alternative Name: EPAS-1

Background: Rabbit Anti-Acetyl-EPAS-1 (K385) Polyclonal Antibody,endothelial PAS domain protein 1,EPAS1 (endothelial PAS domain protein 1) encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in EPAS1 are associated with erythrocytosis familial type 4.,Acetyl-EPAS-1 (K385)

Gene ID: 2034

UniProt: Q99814

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect