Endothelin 2 antibody

Catalog No. ABIN7228354

This Rabbit Polyclonal antibody specifically detects Endothelin 2 in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Endothelin 2 antibody (ABIN7228354)

Target: Endothelin 2 (EDN2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endothelin 2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Endothelin 2 Antibody

Purpose: EDN2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of EDN2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human EDN2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Endothelin 2

Target: Endothelin 2 (EDN2)

Alternative Name: EDN2

Background: Rabbit Anti-EDN2 Polyclonal Antibody,Endothelin-2, ET-2, Preproendothelin-2, PPET2,EDN2 encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. Endothelin 2 is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants.,EDN2

Molecular Weight: observerd band 19kDa

Gene ID: 1907

UniProt: P20800

Pathways: Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones