EPH Receptor A3 antibody

Catalog No. ABIN7220286

This anti-EPH Receptor A3 antibody is a Rabbit Polyclonal antibody detecting EPH Receptor A3 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for EPH Receptor A3 antibody (ABIN7220286)

Target: EPH Receptor A3 (EPHA3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EPH Receptor A3 Antibody

Purpose: EphA3 Polyclonal Antibody

Specificity: EphA3 Polyclonal Antibody detects endogenous levels of EphA3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human EphA3 around the non-phosphorylation site of Y602

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for EPH Receptor A3

Target: EPH Receptor A3 (EPHA3)

Alternative Name: EphA3

Background: Rabbit Anti-EphA3 Polyclonal Antibody,EPHA3, ETK, ETK1, HEK, TYRO4, Ephrin type-A receptor 3, EPH-like kinase 4, EK4, hEK4, HEK, Human embryo kinase, Tyrosine-protein kinase TYRO4, Tyrosine-protein kinase receptor ETK1, Eph-like tyrosine kinase 1,EPHA3 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.,Ephrin type-A receptor 3

Molecular Weight: observerd band 100kDa

Gene ID: 2042

UniProt: P29320

Pathways: RTK Signaling, Regulation of Cell Size