ERLIN1/2 antibody (AA 31-80)

Catalog No. ABIN7226896

The Rabbit Polyclonal anti-ERLIN1/2 antibody has been validated for ELISA and WB. It is suitable to detect ERLIN1/2 in samples from Human, Mouse and Rat.

Quick Overview for ERLIN1/2 antibody (AA 31-80) (ABIN7226896)

Target: ERLIN1/2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERLIN1/2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-ERLIN1/2 Antibody

Binding Specificity: AA 31-80

Purpose: ERLIN1/2 Polyclonal Antibody

Specificity: ERLIN1/2 Polyclonal Antibody detects endogenous levels of ERLIN1/2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from ERLIN1/2 at AA range: 31-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ERLIN1/2

Target: ERLIN1/2

Background: Rabbit Anti-ERLIN1/2 Polyclonal Antibody,Erlin-1 and erlin-2 (SPFH1 and SPFH2) are SPFH domain-containing proteins that belong to the prohibitin family. The N-termal domain of erlin proteins contains ER-targeting sequences responsible for their translocation to the endoplasmic reticulum (ER). In the ER, erlin-1 and erlin-2 specifically associate with the detergent resistant lipid raft microdomain of the membrane. Erlin-1 may be involved in dentritic cell activation and erlin-2 has been shown to regulate the ER-associated degradation (ERAD) pathway by interacting with endogenous substrates and resulting in their polyubiquitination and degradation.,ERLIN1

Molecular Weight: observerd band 40+42kDa