ESRRA antibody (AA 160-240)

Catalog No. ABIN7228432

This anti-ESRRA antibody is a Rabbit Polyclonal antibody detecting ESRRA in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for ESRRA antibody (AA 160-240) (ABIN7228432)

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESRRA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ESRRA Antibody

Binding Specificity: AA 160-240

Purpose: ERR1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ERR1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human ERR1 protein at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Alternative Name: ERR1

Background: Rabbit Anti-ERR1 Polyclonal Antibody,Steroid hormone receptor ERR1, Estrogen receptor-like 1, Estrogen-related receptor alpha, ERR-alpha, Nuclear receptor subfamily 3 group B member 1,The protein encoded by ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for ESRRA.,ERR1

Molecular Weight: observerd band 46kDa

Gene ID: 2101

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha