ETV6 antibody (AA 340-420)

Catalog No. ABIN7217272

The Rabbit Polyclonal anti-ETV6 antibody is suitable to detect ETV6 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF and IHC (p).

Quick Overview for ETV6 antibody (AA 340-420) (ABIN7217272)

Target: ETV6 (Ets Variant 6 (ETV6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETV6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ETV6 Antibody

Binding Specificity: AA 340-420

Purpose: TEL Polyclonal Antibody

Specificity: TEL Polyclonal Antibody detects endogenous levels of TEL protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human TEL at AA range: 340-420

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ETV6

Target: ETV6 (Ets Variant 6 (ETV6))

Alternative Name: TEL

Background: Rabbit Anti-TEL Polyclonal Antibody,ETV6, TEL, TEL1, Transcription factor ETV6, ETS translocation variant 6, ETS-related protein Tel1, Tel,ETV6 encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.,Transcription factor ETV6

Molecular Weight: observerd band 53kDa

Gene ID: 2120

UniProt: P41212