ETV6 antibody

Catalog No. ABIN7220400

This anti-ETV6 antibody is a Rabbit Polyclonal antibody detecting ETV6 in WB and ELISA. Suitable for Human.

Quick Overview for ETV6 antibody (ABIN7220400)

Target: ETV6 (Ets Variant 6 (ETV6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETV6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ETV6 Antibody

Purpose: TEL Polyclonal Antibody

Specificity: TEL Polyclonal Antibody detects endogenous levels of TEL protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human TEL around the non-phosphorylation site of S257

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ETV6

Target: ETV6 (Ets Variant 6 (ETV6))

Alternative Name: TEL

Background: Rabbit Anti-TEL Polyclonal Antibody,ETV6, TEL, TEL1, Transcription factor ETV6, ETS translocation variant 6, ETS-related protein Tel1, Tel,ETV6 encodes an ETS family transcription factor. The product of ETV6 contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. ETV6 is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.,Transcription factor ETV6

Molecular Weight: observerd band 55kDa

Gene ID: 2120

UniProt: P41212