FAT Atypical Cadherin 2 (FAT2) antibody

Catalog No. ABIN7228490

The Rabbit Polyclonal anti- antibody has been validated for IHC (p). It is suitable to detect in samples from Human, Mouse and Rat.

Quick Overview for FAT Atypical Cadherin 2 (FAT2) antibody (ABIN7228490)

Target: FAT Atypical Cadherin 2 (FAT2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Purpose: FAT2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FAT2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human FAT2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:300).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details

Target: FAT Atypical Cadherin 2 (FAT2)

Alternative Name: FAT2

Background: Rabbit Anti-FAT2 Polyclonal Antibody,Protocadherin Fat 2, hFat2, Cadherin family member 8, Multiple epidermal growth factor-like domains protein 1, Multiple EGF-like domains protein 1,FAT2 gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development.,FAT2

Molecular Weight: observerd band 478kDa

Gene ID: 2196

UniProt: Q9NYQ8