FOSB antibody (pSer27)

Catalog No. ABIN7220740

This anti-FOSB antibody is a Rabbit Polyclonal antibody detecting FOSB in WB, ELISA, IF and IHC (p). Suitable for Human and Mouse.

Quick Overview for FOSB antibody (pSer27) (ABIN7220740)

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOSB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FOSB Antibody

Binding Specificity: pSer27

Purpose: Fos B (phospho Ser27) Polyclonal Antibody

Specificity: Phospho-Fos B (S27) Polyclonal Antibody detects endogenous levels of Fos B protein only when phosphorylated at S27.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Fos B Phospho-Ser27

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for FOSB

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Alternative Name: Fos B

Background: Rabbit Anti-Fos B (phospho Ser27) Polyclonal Antibody,FOSB, G0S3, Protein fosB, G0/G1 switch regulatory protein 3,The Fos gene family consists of 4 members: fOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for FOSB.,Protein fosB

Molecular Weight: observerd band 35kDa

Gene ID: 2354

UniProt: P53539