Fc gamma RII (CD32) (pTyr292) antibody
Quick Overview for Fc gamma RII (CD32) (pTyr292) antibody (ABIN7220486)
Target
See all Fc gamma RII (CD32) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pTyr292
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Purpose
- CD32 (phospho Tyr292) Polyclonal Antibody
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Specificity
- Phospho-CD32 (Y292) Polyclonal Antibody detects endogenous levels of CD32 protein only when phosphorylated at Y292.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from human CD32 Phospho-Tyr292
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Fc gamma RII (CD32)
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Alternative Name
- CD32
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Background
- Rabbit Anti-CD32 (phospho Tyr292) Polyclonal Antibody,FCGR2B, CD32, FCG2, IGFR2, Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, CD antigen CD32,The Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.,Low affinity immunoglobulin gamma Fc region receptor II-b
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Molecular Weight
- observerd band 32kDa
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Gene ID
- 2213
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UniProt
- P31994
Target
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