FEV antibody (N-Term)

Catalog No. ABIN7223316

This Rabbit Polyclonal antibody specifically detects FEV in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for FEV antibody (N-Term) (ABIN7223316)

Target: FEV (FEV (ETS Oncogene Family) (FEV))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEV antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FEV Antibody

Binding Specificity: N-Term

Purpose: FEV Polyclonal Antibody

Specificity: FEV Polyclonal Antibody detects endogenous levels of FEV protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human FEV

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for FEV

Target: FEV (FEV (ETS Oncogene Family) (FEV))

Alternative Name: FEV

Background: Rabbit Anti-FEV Polyclonal Antibody,FEV, PET1, Protein FEV, Fifth Ewing variant protein, PC12 ETS domain-containing transcription factor 1, PC12 ETS factor 1, Pet-1,FEV (FEV, ETS transcription factor) belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. FEV is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, FEV is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.,Protein FEV

Molecular Weight: observerd band 25kDa

Gene ID: 54738

UniProt: Q99581