Flk-1/Flt-4 (pTyr1054) antibody

Catalog No. ABIN7222030

The Rabbit Polyclonal anti-Flk-1/Flt-4 antibody is suitable to detect Flk-1/Flt-4 in samples from Human, Mouse and Rat. It has been validated for ELISA and IHC (p).

Quick Overview for Flk-1/Flt-4 (pTyr1054) antibody (ABIN7222030)

Target: Flk-1/Flt-4

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: pTyr1054

Purpose: Flk-1/Flt-4 (phospho Tyr1054/Y1063) Polyclonal Antibody

Specificity: Phospho-Flk-1/Flt-4 (Y1054/Y1063) Polyclonal Antibody detects endogenous levels of Flk-1/Flt-4 protein only when phosphorylated at Y1054/Y1063.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Flk-1/Flt-4 Phospho-Tyr1054/Y1063

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details

Target: Flk-1/Flt-4

Background: Rabbit Anti-Flk-1/Flt-4 (phospho Tyr1054/Y1063) Polyclonal Antibody,KDR, FLK1, VEGFR2, Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1, CD antigen CD309, FLT4, VEGFR3, Vascular endothelial growth,VEGF R1 is one of the five receptor tyrosine kinases (RTKs) (Flt-1, KDR/Flk-1, Flt-4, tie-1, and tek/tie-2) whose expression is almost exclusively restricted to the endothelial cells. Tie-1 and tek/tie-2 define a new class of RTKs containing two immunoglobulin-like domains, three EGF homology domains and three fibronectin type III domains in their extracellular regions. Flt-1, KDR/Flk-1 and Flt-4 are members of the class III subfamily of RTKs containing seven immunoglobulin-like repeats in their extracellular domains. All five RTKs are likely to play central roles in vasculogenesis and angiogenesis.,Vascular endothelial growth factor receptor 2

Gene ID: 3791, 2324