FOLR2 antibody

Catalog No. ABIN7228570

The Rabbit Polyclonal anti-FOLR2 antibody has been validated for WB and ELISA. It is suitable to detect FOLR2 in samples from Human and Mouse.

Quick Overview for FOLR2 antibody (ABIN7228570)

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FOLR2 Antibody

Purpose: FOLR2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FOLR2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human FOLR2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for FOLR2

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Alternative Name: FOLR2

Background: Rabbit Anti-FOLR2 Polyclonal Antibody,Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP,FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. FOLR2 (Folate Receptor Beta) is a Protein Coding gene. Diseases associated with FOLR2 include Neural Tube Defects and Rheumatoid Arthritis. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors.,FOLR2

Molecular Weight: observerd band 28kDa

Gene ID: 2350

UniProt: P14207

Pathways: Dicarboxylic Acid Transport