FOXM1 antibody (AA 190-270)

Catalog No. ABIN7228578

This Rabbit Polyclonal antibody specifically detects FOXM1 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for FOXM1 antibody (AA 190-270) (ABIN7228578)

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FOXM1 Antibody

Binding Specificity: AA 190-270

Purpose: FOXM1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FOXM1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human FOXM1 protein at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for FOXM1

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Alternative Name: FOXM1

Background: Rabbit Anti-FOXM1 Polyclonal Antibody,Forkhead box protein M1, Forkhead-related protein FKHL16, Hepatocyte nuclear factor 3 forkhead homolog 11, HFH-11, HNF-3/fork-head homolog 11, M-phase phosphoprotein 2, MPM-2 reactive phosphoprotein 2, Transcription factor Trident,Winged-helix factor from INS-1 cells,FOXM1 (Forkhead Box M1) is a Protein Coding gene. Diseases associated with FOXM1 include Meckel's Diverticulum and Balanoposthitis. Among its related pathways are DNA Damage and Regulation of PLK1 Activity at G2/M Transition. The protein encoded by FOXM1 is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for FOXM1.,FOXM1

Molecular Weight: observerd band 83kDa

Gene ID: 2305

UniProt: Q08050

Pathways: Positive Regulation of Response to DNA Damage Stimulus