FPR2 antibody (AA 130-210)

Catalog No. ABIN7228588

The Rabbit Polyclonal anti-FPR2 antibody has been validated for WB and ELISA. It is suitable to detect FPR2 in samples from Human.

Quick Overview for FPR2 antibody (AA 130-210) (ABIN7228588)

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FPR2 Antibody

Binding Specificity: AA 130-210

Purpose: FPR2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FPR2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human FPR2 protein at AA range: 130-210

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for FPR2

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Alternative Name: FPR2

Background: Rabbit Anti-FPR2 Polyclonal Antibody,N-formyl peptide receptor 2, FMLP-related receptor I, FMLP-R-I, Formyl peptide receptor-like 1, HM63, Lipoxin A4 receptor, LXA4 receptor, RFP,FPR2 (Formyl Peptide Receptor 2) is a Protein Coding gene. Diseases associated with FPR2 include Prion Disease. Among its related pathways are Akt Signaling and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and N-formyl peptide receptor activity. An important paralog of this gene is FPR3. Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).,FPR2

Molecular Weight: observerd band 38kDa

Gene ID: 2358

UniProt: P25090