FZD3 antibody (AA 110-190)

Catalog No. ABIN7214954

This anti-FZD3 antibody is a Rabbit Polyclonal antibody detecting FZD3 in WB, ELISA and IF. Suitable for Human and Mouse.

Quick Overview for FZD3 antibody (AA 110-190) (ABIN7214954)

Target: FZD3 (Frizzled Family Receptor 3 (FZD3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-FZD3 Antibody

Binding Specificity: AA 110-190

Purpose: Frizzled-3 Polyclonal Antibody

Specificity: Frizzled-3 Polyclonal Antibody detects endogenous levels of Frizzled-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Frizzled-3 at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for FZD3

Target: FZD3 (Frizzled Family Receptor 3 (FZD3))

Alternative Name: Frizzled-3

Background: Rabbit Anti-Frizzled-3 Polyclonal Antibody,FZD3, Frizzled-3, Fz-3, hFz3,FZD3 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of Frizzled-3 is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. FZD3 is a susceptibility locus for schizophrenia.,Frizzled-3

Molecular Weight: observerd band 76kDa

Gene ID: 7976

UniProt: Q9NPG1

Pathways: WNT Signaling, Tube Formation