FKRP antibody (AA 10-90)
Quick Overview for FKRP antibody (AA 10-90) (ABIN7225044)
Target
See all FKRP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 10-90
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Purpose
- FKRP Polyclonal Antibody
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Specificity
- FKRP Polyclonal Antibody detects endogenous levels of FKRP protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the N-terminal region of human FKRP at AA range: 10-90
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FKRP (Fukutin Related Protein (FKRP))
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Alternative Name
- FKRP
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Background
- Rabbit Anti-FKRP Polyclonal Antibody,FKRP, Fukutin-related protein,FKRP (fukutin related protein) encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in FKRP have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of FKRP have been described, but the full-length nature of some of these variants has not been determined.,Fukutin-related protein
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Molecular Weight
- observerd band 50kDa
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Gene ID
- 79147
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UniProt
- Q9H9S5
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Pathways
- Regulation of Carbohydrate Metabolic Process
Target
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