FYB antibody (AA 620-700)

Catalog No. ABIN7214972

This Rabbit Polyclonal antibody specifically detects FYB in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FYB antibody (AA 620-700) (ABIN7214972)

Target: FYB (FYN-Binding Protein (FYB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FYB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FYB Antibody

Binding Specificity: AA 620-700

Purpose: Fyb Polyclonal Antibody

Specificity: Fyb Polyclonal Antibody detects endogenous levels of Fyb protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Fyb at AA range: 620-700

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for FYB

Target: FYB (FYN-Binding Protein (FYB))

Alternative Name: Fyb

Background: Rabbit Anti-Fyb Polyclonal Antibody,FYB, SLAP130, FYN-binding protein, Adhesion and degranulation promoting adaptor protein, ADAP, FYB-120/130, p120/p130, FYN-T-binding protein, SLAP-130, SLP-76-associated phosphoprotein,FYN-binding protein encoded by FYB is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. FYN-binding protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene.,FYN-binding protein

Molecular Weight: observerd band 85kDa

Gene ID: 2533

UniProt: O15117

Pathways: TCR Signaling, Protein targeting to Nucleus