GPS2 antibody (AA 30-110)

Catalog No. ABIN7221282

This anti-GPS2 antibody is a Rabbit Polyclonal antibody detecting GPS2 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for GPS2 antibody (AA 30-110) (ABIN7221282)

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GPS2 Antibody

Binding Specificity: AA 30-110

Purpose: GPS2 Polyclonal Antibody

Specificity: GPS2 Polyclonal Antibody detects endogenous levels of GPS2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human GPS2 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GPS2

Target: GPS2 (G Protein Pathway Suppressor 2 (GPS2))

Alternative Name: GPS2

Background: Rabbit Anti-GPS2 Polyclonal Antibody,GPS2, G protein pathway suppressor 2, GPS-2,GPS2 encodes G protein pathway suppressor 2 involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.,G protein pathway suppressor 2

Molecular Weight: observerd band 40kDa

Gene ID: 2874

UniProt: Q13227