MRGPRX2 antibody (AA 250-330)

Catalog No. ABIN7229756

The Rabbit Polyclonal anti-MRGPRX2 antibody (ABIN7229756) specifically detects MRGPRX2 in ELISA and WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for MRGPRX2 antibody (AA 250-330) (ABIN7229756)

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRGPRX2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-MRGPRX2 Antibody

Binding Specificity: AA 250-330

Purpose: MRGX2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MRGX2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human MRGX2 protein at AA range: 250-330

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for MRGPRX2

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Alternative Name: MRGX2

Background: Rabbit Anti-MRGX2 Polyclonal Antibody,Mas-related G-protein coupled receptor member X2,Mast cell-specific receptor for basic secretagogues, i.e. Cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed: 25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (By similarity). Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.,MRGX2

Molecular Weight: observerd band 36kDa

Gene ID: 117194

UniProt: Q96LB1