Gl Syn (Internal Region) antibody
Quick Overview for Gl Syn (Internal Region) antibody (ABIN7217622)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Internal Region
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Purpose
- Gl Syn Polyclonal Antibody
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Specificity
- Gl Syn Polyclonal Antibody detects endogenous levels of Gl Syn protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human Gl Syn
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Gl Syn
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Background
- Rabbit Anti-Gl Syn Polyclonal Antibody,GLUL, GLNS, Glutamine synthetase, GS, Glutamate decarboxylase, Glutamate--ammonia ligase,Glutamine synthetase encoded by GLUL belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.,Glutamine synthetase
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Molecular Weight
- observerd band 42kDa
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Gene ID
- 2752
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UniProt
- P15104
Target
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