Glucuronidase beta antibody (AA 290-370)

Catalog No. ABIN7221406

The Rabbit Polyclonal anti-Glucuronidase beta antibody has been validated for WB and ELISA. It is suitable to detect Glucuronidase beta in samples from Human, Mouse and Rat.

Quick Overview for Glucuronidase beta antibody (AA 290-370) (ABIN7221406)

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glucuronidase beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Glucuronidase beta Antibody

Binding Specificity: AA 290-370

Purpose: Glucuronidase β Polyclonal Antibody

Specificity: Glucuronidase β Polyclonal Antibody detects endogenous levels of Glucuronidase β protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Glucuronidase beta at AA range: 290-370

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Glucuronidase beta

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Alternative Name: Glucuronidase beta

Background: Rabbit Anti-Glucuronidase β Polyclonal Antibody,GUSB, Beta-glucuronidase, Beta-G1,GUSB encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.,Beta-glucuronidase

Molecular Weight: observerd band 78kDa

Gene ID: 2990

UniProt: P08236

Pathways: Glycosaminoglycan Metabolic Process