GAS2 antibody

Catalog No. ABIN7228616

This anti-GAS2 antibody is a Rabbit Polyclonal antibody detecting GAS2 in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for GAS2 antibody (ABIN7228616)

Target: GAS2 (Growth Arrest-Specific 2 (GAS2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GAS2 Antibody

Purpose: GAS2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GAS2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human GAS2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GAS2

Target: GAS2 (Growth Arrest-Specific 2 (GAS2))

Alternative Name: GAS2

Background: Rabbit Anti-GAS2 Polyclonal Antibody,Growth arrest-specific protein 2, GAS-2,The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants. GAS2 (Growth Arrest Specific 2) is a Protein Coding gene. Diseases associated with GAS2 include Gnathodiaphyseal Dysplasia. Among its related pathways are p70S6K Signaling and Akt Signaling. An important paralog of this gene is GAS2L3.,GAS2

Molecular Weight: observerd band 34kDa

Gene ID: 2620

UniProt: O43903

Pathways: Caspase Cascade in Apoptosis