GDF10 antibody
Quick Overview for GDF10 antibody (ABIN7227490)
Target
See all GDF10 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- BMP3B Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of BMP3B protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human BMP3B protein
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- GDF10 (Growth Differentiation Factor 10 (GDF10))
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Alternative Name
- BMP3B
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Background
- Rabbit Anti-BMP3B Polyclonal Antibody,Growth/differentiation factor 10, GDF-10, Bone morphogenetic protein 3B, BMP-3B, Bone-inducing protein, BIP,GDF10 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of GDF10 is associated with oral cancer.,BMP3B
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Molecular Weight
- observerd band 52kDa
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Gene ID
- 2662
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UniProt
- P55107
Target
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