GBP5 antibody (Internal Region)

Catalog No. ABIN7219352

This anti-GBP5 antibody is a Rabbit Polyclonal antibody detecting GBP5 in ELISA and IHC (p). Suitable for Human.

Quick Overview for GBP5 antibody (Internal Region) (ABIN7219352)

Target: GBP5 (Guanylate Binding Protein 5 (GBP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GBP5 Antibody

Binding Specificity: Internal Region

Purpose: GBP5 Polyclonal Antibody

Specificity: GBP5 Polyclonal Antibody detects endogenous levels of GBP5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human GBP5

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GBP5

Target: GBP5 (Guanylate Binding Protein 5 (GBP5))

Alternative Name: GBP5

Background: Rabbit Anti-GBP5 Polyclonal Antibody,GBP5, Guanylate-binding protein 5, GBP-TA antigen, GTP-binding protein 5, GBP-5, Guanine nucleotide-binding protein 5,GBP5 (Guanylate Binding Protein 5) is a Protein Coding gene. Diseases associated with GBP5 include chronic active epstein-barr virus infection. Among its related pathways are Immune System and Interferon gamma signaling. GO annotations related to this gene include identical protein binding and GTPase activity. An important paralog of this gene is GBP7. s an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed: 22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed: 20180847).,Guanylate-binding protein 5

Molecular Weight: observerd band 66kDa

Gene ID: 115362

UniProt: Q96PP8