GUCY1A1 antibody (Internal Region)

Catalog No. ABIN7215040

This Rabbit Polyclonal antibody specifically detects GUCY1A1 in WB, ELISA and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for GUCY1A1 antibody (Internal Region) (ABIN7215040)

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCY1A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GUCY1A1 Antibody

Binding Specificity: Internal Region

Purpose: GCS-α-1 Polyclonal Antibody

Specificity: GCS-α-1 Polyclonal Antibody detects endogenous levels of GCS-α-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human GCS-alpha-1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GUCY1A1

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Alternative Name: GCS-alpha-1

Background: Rabbit Anti-GCS-α-1 Polyclonal Antibody,GUCY1A3, GUC1A3, GUCSA3, GUCY1A1, Guanylate cyclase soluble subunit alpha-3, GCS-alpha-3, GCS-alpha-1, Soluble guanylate cyclase large subunit,Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. Guanylate cyclase soluble subunit alpha-3 encoded by GUCY1A3 is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.,Guanylate cyclase soluble subunit alpha-3

Molecular Weight: observerd band 77kDa

Gene ID: 2982

UniProt: Q02108

Pathways: Myometrial Relaxation and Contraction