GUCY1B2 antibody (N-Term)

Catalog No. ABIN7221398

The Rabbit Polyclonal anti-GUCY1B2 antibody has been validated for ELISA and IHC (p). It is suitable to detect GUCY1B2 in samples from Human, Mouse and Rat.

Quick Overview for GUCY1B2 antibody (N-Term) (ABIN7221398)

Target: GUCY1B2 (Guanylate Cyclase 1, Soluble, beta 2 (GUCY1B2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCY1B2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GUCY1B2 Antibody

Binding Specificity: N-Term

Purpose: GCS-β-2 Polyclonal Antibody

Specificity: GCS-β-2 Polyclonal Antibody detects endogenous levels of GCS-β-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human GCS-beta-2

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for GUCY1B2

Target: GUCY1B2 (Guanylate Cyclase 1, Soluble, beta 2 (GUCY1B2))

Alternative Name: GCS-beta-2

Background: Rabbit Anti-GCS-β-2 Polyclonal Antibody,GUCY1B2, Guanylate cyclase soluble subunit beta-2, GCS-beta-2,Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.,Guanylate cyclase soluble subunit beta-2

Molecular Weight: observerd band 70kDa

Gene ID: 2974

UniProt: O75343