HSP70 antibody (acLys246)

Catalog No. ABIN7212654

This Rabbit Polyclonal antibody specifically detects HSP70 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for HSP70 antibody (acLys246) (ABIN7212654)

Target: HSP70 (Heat Shock Protein 70 (HSP70))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP70 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HSP70 Antibody

Binding Specificity: acLys246

Purpose: HSP70 (Acetyl Lys246) Polyclonal Antibody

Specificity: Acetyl-HSP70 (K246) Polyclonal Antibody detects endogenous levels of HSP70 protein only when non-acetylation at K246.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human HSP70 around the acetylation site of K246

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for HSP70

Target: HSP70 (Heat Shock Protein 70 (HSP70))

Alternative Name: HSP70

Background: Rabbit Anti-HSP70 (Acetyl Lys246) Polyclonal Antibody,HSPA1A, HSPA1, HSPA1B, Heat shock 70 kDa protein 1A/1B, Heat shock 70 kDa protein 1/2, HSP70-1/HSP70-2, HSP70.1/HSP70.2,HSPA1A encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, heat shock protein family A (Hsp70) member 1A stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. HSPA1A is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.,Heat shock 70 kDa protein 1A

Molecular Weight: observerd band 70kDa

Gene ID: 3303, 3304

UniProt: P08107