HSP90 antibody (acLys435)

Catalog No. ABIN7212600

The Rabbit Polyclonal anti-HSP90 antibody (ABIN7212600) specifically detects HSP90 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for HSP90 antibody (acLys435) (ABIN7212600)

Target: HSP90 (Heat Shock Protein 90 (HSP90))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP90 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HSP90 Antibody

Binding Specificity: acLys435

Purpose: HSP 90 (Acetyl Lys435) Polyclonal Antibody

Specificity: Acetyl-HSP 90 (K435) Polyclonal Antibody detects endogenous levels of HSP 90 protein only when acetylated at K435.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the human HSP 90 around the acetylation site of K435

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for HSP90

Target: HSP90 (Heat Shock Protein 90 (HSP90))

Alternative Name: HSP 90

Background: Rabbit Anti-HSP 90 (Acetyl Lys435) Polyclonal Antibody,HSP90AA1, HSP90A, HSPC1, HSPCA, Heat shock protein HSP 90-alpha, Heat shock 86 kDa, HSP 86, HSP86, Renal carcinoma antigen NY-REN-38,The protein encoded by HSP90AA1 is an inducible molecular chaperone that functions as a homodimer heat shock protein 90 alpha family class A member 1 aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for HSP90AA1.,Heat shock protein HSP 90-alpha

Molecular Weight: observerd band 85kDa

Gene ID: 3320

UniProt: P07900

Pathways: M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals